HRN_VP1d [FBbt_00047226]

Adult hygrosensory neuron that expresses the humidity-sensing Ionotropic receptor (Ir) 40a, and the co-receptors Ir93a and Ir25a, and innervates the antennal lobe glomerulus VP1d (Enjin et al, 2016; Knecht et al., 2016; Marin et al., 2020). It receives sensory input in the blunt-tipped sensilla of chamber II of the sacculus and its projections remain strictly ipsilateral (Silbering et al., 2011; Marin et al., 2020; Schlegel et al., 2021). It is activated by dry air (to a lesser extent than the VP4 Ir40a neurons) (Knecht et al., 2016) and by large decreases in temperature (Enjin et al., 2016), which may collectively correspond to detection of evaporative cooling (Marin et al., 2020). It develops from an Nab precursor (Benton et al., 2025). There are around 7-9 of these cells per hemisphere (Marin et al., 2020).
HRN_VP1d HRN_VP1d HRN_VP1d HRN_VP1d

HRN_VP1d

ID: FBbt_00047226

Adult Hygrosensory system Nervous system Sensory neuron Thermosensory system

Adult hygrosensory neuron that expresses the humidity-sensing Ionotropic receptor (Ir) 40a, and the co-receptors Ir93a and Ir25a, and innervates the antennal lobe glomerulus VP1d (Enjin et al, 2016; Knecht et al., 2016; Marin et al., 2020). It receives sensory input in the blunt-tipped sensilla of chamber II of the sacculus and its projections remain strictly ipsilateral (Silbering et al., 2011; Marin et al., 2020; Schlegel et al., 2021). It is activated by dry air (to a lesser extent than the VP4 Ir40a neurons) (Knecht et al., 2016) and by large decreases in temperature (Enjin et al., 2016), which may collectively correspond to detection of evaporative cooling (Marin et al., 2020). It develops from an Nab precursor (Benton et al., 2025). There are around 7-9 of these cells per hemisphere (Marin et al., 2020).

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## Classification

Relationships

Alternative Names

Synonym Scope Reference
VP1dRN exact synonym Marin et al., 2020
HRN_VP1d exact synonym Bates et al., 2025
HRN_VP1d exact synonym Berg et al., 2025
HRN_VP1d exact synonym Marin et al., 2020
adult olfactory receptor neuron Ir40a VP1 related synonym
HRN_VP1d exact synonym Schlegel et al., 2024
HRN_VP1d exact synonym Scheffer et al., 2020

List all available images of HRN_VP1d (88 total)

Thumbnail Name Tags
HRN_VP1d_L (MaleCNS:132166) Nervous_system, Hygrosensory_system, Sensory_neuron, Thermosensory_system, Adult, Cholinergic
HRN_VP1d_L (MaleCNS:73560) Nervous_system, Hygrosensory_system, Sensory_neuron, Thermosensory_system, Adult, Cholinergic
HRN_VP1d_L (MaleCNS:917516) Nervous_system, Hygrosensory_system, Sensory_neuron, Thermosensory_system, Adult, Cholinergic
HRN_VP1d_R (MaleCNS:515070) Nervous_system, Hygrosensory_system, Sensory_neuron, Thermosensory_system, Adult, Cholinergic
HRN_VP1d_R (MaleCNS:521157) Nervous_system, Hygrosensory_system, Sensory_neuron, Thermosensory_system, Adult, Cholinergic

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Downstream connectivity classes for HRN_VP1d (71 total)

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Upstream connectivity classes for HRN_VP1d (28 total)

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